Publications 2021

5

Mesenchymal stem cell extracellular vesicles as adjuvant to bone marrow stimulation in chondral defect repair in a minipig model

Kris T C Hede , Bjørn B Christensen , Morten L Olesen , Jesper Skovhus Thomsen , Casper B Foldager, Wei Seong Toh , Sai Kiang Lim , Martin C Lind              

5

Mesenchymal Stromal Cell (MSC)-derived Small Extracellular Vesicles as Next-generation Therapeutics for Cartilage Regeneration

Kristeen Ye Wen Teo, Shipin Zhang,

Wei Seong Toh

 

5

Intra-articular injections of mesenchymal stem cells without adjuvant therapies for knee osteoarthritis: a systematic review and meta-analysis

Si Heng Sharon Tan , Yiu Tsun Kwan , Wei Jian Neo , Jia Yan Chong , Tze Yin Joshua Kuek , Jun Ze Fabian See , Keng Lin Wong , Wei Seong Toh , James Hoi Po Hui          

5

Mesenchymal stromal cell-derived small extracellular vesicles promote physeal regeneration and reduce growth arrest following growth plate injury in rats

S Zhang, S Tan, K Wong, S Chuah, Y Cheow, R Lai, S Lim, J Hui, W Toh

 

5

Mesenchymal stromal cell-derived small extracellular vesicles promote osteoarthritic joint repair and pain recovery through immunomodulation

Teo, S Zhang, S Chuah, R Lai, S Lim, W Toh          

5

MSC exosomes enhance dental pulp cell functions through CD73/ecto-5’-nucleotidase activity

J Shi, S Wang, S Zhang, R Lai, V Rosa, S Lim, MS Duggal, W Toh

 

5

Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles

Mario Gimona , Maria Felice Brizzi , Andre Boon Hwa Choo , Massimo Dominici , Sean M Davidson , Johannes Grillari , Dirk M Hermann , Andrew F Hill , Dominique de Kleijn , Ruenn Chai Lai , Charles P Lai , Rebecca Lim , Marta Monguió-Tortajada , Maurizio Muraca , Takahiro Ochiya, Luis A Ortiz , Wei Seong Toh , Yong Weon Yi , Kenneth W Witwer , Bernd Giebel , Sai Kiang Lim 

 

5

Mesenchymal Stem Cell Exosomes for Cartilage Regeneration: A Systematic Review of Preclinical In Vivo Studies

SSH Tan, CKE Tjio, JRY Wong, KL Wong, JRJ Chew, JHP Hui, WS Toh

 

5

Extracellular Vesicle Treatment, Epigenetic Modification and Cell Reprogramming to Promote Bone and Cartilage Regeneration

YA Pei, Y Dong, TC He, WJ Li, WS Toh, M Pei

 

5

Use of exosomes to promote or enhance hair growth

SK Lim, MSW Yeo, TS Chen, RC Lai

 

5

MSC exosomes promote osteochondral repair in a translational porcine model

W Toh, S Zhang, K Wong, X Ren, R Lai, S Lim, J Hui

 

5

Mesenchymal stromal cell-derived small extracellular vesicles promote angio-osteogenesis and modulate macrophage polarization to enhance bone regeneration

S Chuah, C Yong, J Chew, Y Cheow, K Teo, S Zhang, R Lai, R Wong, …

 

5

Assessment of tumorigenic potential in mesenchymal-stem/stromal-cell-derived small extracellular vesicles (MSC-sEV)

TT Tan, RC Lai, J Padmanabhan, WK Sim, ABH Choo, SK Lim

 

5

Mesenchymal stem cell‐derived extracellular vesicles reduce senescence and extend health span in mouse models of aging

A Dorronsoro, FE Santiago, D Grassi, T Zhang, RC Lai, SJ McGowan, …

 

5

Topical application of mesenchymal stem cell exosomes alleviates the imiquimod induced psoriasis-like inflammation

B Zhang, RC Lai, WK Sim, ABH Choo, EB Lane, SK Lim